职务：

广州医科大学肿瘤研究所所长

职称：

教授

研究方向：

自噬与疾病。

科研项目：

1、细胞稳态与癌症研究实验室，项目编号:2019KSYS004,省教育厅项目，2020.1.1-2022.12.31,100万

代表性学术论文：

1、Wei-Chung Chiang #,Yongjie Wei# ,Yi-Chun Kuo ,Shuguang Wei,Anwu Zhou,Zhongju Zou,Jenna Yehl,Matthew J Ranaghan ,Adam Skepner,Joshua A Bittker,Jose R Perez, Bruce A Posner, Beth Levine;ACS chemical biology；High-throughput screens to identify autophagy inducers that function by disrupting Beclin 1/Bcl-2 binding；ACS chemical biology;2018 Aug 17;13(8):2247-2260
2、Yongjie Wei,Wei-Chung Chiang,Rhea Sumpter Jr,Prashant Mishra,Beth Levine; Prohibitin 2 is an inner mitochondrial membrane mitophagy receptor;cell;2017 Jan 12;168(1-2):224-238.
3、Pedro JM #, Wei Y #, Sica V, Maiuri MC, Zou Z, Kroemer G, Levine B. 2015. BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. Autophagy, 11(3):452-9
4、Yongjie Wei ,Zhenyi An ,Zhongju Zou ,Rhea Sumpter,Minfei Su ,Xiao Zang , Sangita Sinha ,Matthias Gaestel,Beth Levine; Elife.;The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation; 2015 Feb 18;4:e05289
5、Wei Y, Zou Z , Becker N, Anderson M, Sumpter R, Borczuk A, Xiao G, Peyton M, Minna J, Bhagat G, and Levine B. EGFR-Mediated Phosphorylation of Beclin 1 in Autophagy Suppression, Tumor Progression and Tumor Chemoresistance. Cell. 2013, 154(6):1269-84 .
6、Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell. 2008 Jun 20;30(6):678-88.
7、Wei Y, Sinha S, Levine B. Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation Autophagy. 2008 Oct;4(7):949-51

联系方式：

Email: weiyongjie@gzhmu.edu.cn