科研项目
1、间充质干细胞外泌体递送LncRNA SNHG5调控肺成纤维细胞衰老缓解肺纤维化的作用及机制研究，2021年，54万，主持
2、EP300/miR-662/Fis1信号通路诱导肺成纤维细胞衰老促进特发性肺纤维化的作用及机制研究，2022年，10万，主持
3、基于创新的外泌体提取检测技术联合影像组学建立早期预测肺纤维化进展的模型，2024年，40万，主持
4、基于多组学融合的间质性肺疾病精准诊断与分层管理体系研究，2025年，1764万，主持
5、Radiomics-Proteomics Integration Predicts Disease Behavior in Pulmonary Fibrosis，2025年，20万，主持
代表性成果
1、Dietary intake and BCAA metabolism regulate pulmonary fibrosis through KDM4A‑mediated epigenetic remodeling in male mice，Nature Communications，IF：18.1，共同通讯（第二）
2、Methylated circPTK2 as a driver of fibroblast activation in pulmonary fibrosis，Molecular Therapy，IF：11.4，共同通讯（第三）
3、The exosomal protein biomarkers auxiliary in diagnosis of interstitial lung disease，Respiratory Research，IF：7.162，共同通讯（第二）
4、Effectiveness and safety of tofacitinib versus calcineurin inhibitor in interstitial lung disease secondary to anti‑MDA5‑positive dermatomyositis: a multicentre cohort study，European Respiratory Journal，IF：23.8，共同通讯（第三）
5、Pulmonary intravascular large B‑cell lymphoma misdiagnosed as allergic pneumonia: a case report and literature review，Therapeutic Advances in Respiratory Disease，IF：3.2，通讯作者
6、miR‑205‑5p accelerates lung fibroblast senescence in IPF patients via mediation of mitochondrial dynamics，Mitochondrion，IF：5.7，通讯作者
7、Delayed Viral Clearance Accompanied by Early Impaired Humoral and Virus‑Specific T‑Cell Response in Patients with Coronavirus Disease 2019 and Interstitial Lung Disease，Vaccines (Basel)，IF：3.5，主通讯作者
8、Mortality Risk Prediction in Patients With Antimelanoma Differentiation‑Associated, Gene 5 Antibody‑Positive, Dermatomyositis‑Associated Interstitial Lung Disease: Algorithm Development and Validation，J Med Internet Res，IF：8.2，共同通讯（第四）
9、Pretreatment with growth differentiation factor 15 augments cardioprotection by mesenchymal stem cells in myocardial infarction by improving their survival，Stem Cell Research & Therapy，IF：7.8，共同第一（第三）
10、iPSC‑MSC‑derived exosomes attenuate pulmonary fibrosis by inhibiting pulmonary fibroblast activation via delivery of TRIM31，International Journal of Biological Sciences，IF：8.7，共同通讯（第二）
11、GDF15‑Treated iPSC‑MSC‑Derived Exosomes Alleviate Fibrosis Post‑Myocardial Infarction via the Repression of the MFAP4/ERK/Drp1，FASEB J，IF：4.3，共同第一（第二）
12、Characterizing the lavage and serum cytokine profiles of interstitial pneumonia with autoimmune features and their implications for progressive fibrosis，Rheumatology (Oxford)，IF：4.7，共同通讯（第二）
13、Complex Involvement of the Extracellular Matrix, Immune Effect, and Lipid Metabolism in the Development of Idiopathic Pulmonary Fibrosis，Frontiers in Molecular Biosciences，IF：4.4，共同通讯（第三）
14、Tropheryma whipplei in interstitial lung disease: A case series.，Respir Med Case Rep，IF：0.7，通讯作者
郭旭光
