代表性成果
1、Perturbing TET2 condensation promotes aberrant genome-wide DNA methylation and curtails leukemia cell growth ;Nature Cell Biology.2024;IF:21.3, I区(倒数第二共通讯)
2、Hong T, Li J, et al. TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells. Nature Aging. 2023 Oct 26:1-4.(共一/共通讯)
3、Yang P, Luo Q, Wang X, Fang Q, Fu Z, Li J, et al. Comprehensive analysis of fibroblast activation protein expression in interstitial lung diseases. American Journal of Respiratory and Critical Care Medicine. 2023 Jan 15;207(2):160-72.(共一)
4、Li J, Hong T, et al. Aberrant DNA hydroxymethylation reshapes transcription factor binding in myeloid neoplasms. Clinical epigenetics. 2022 Dec;14(1):1-4. (第一作者)
5、Zhao S, Li J, Zhang H, et al. Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas. Nature communications. 2022 Nov 5;13(1):6689. (共一)
6、Fang S, Cui D, …, Li J, Huang Y. Ten-Eleven Translocation Ablation Impairs Cardiac Differentiation of Mouse Embryonic Stem Cells. Stem Cells. 2022 Mar 1;40(3):260-72. (倒数第二共同通讯)
7、Chen YS, Li J, et al. Dietary spinach reshapes the gut microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics. Gut Microbes. 2021 Jan 1;13(1):1972756. (共一)
8、Yin Y, Li J, Li J, et al. LiBis: an ultrasensitive alignment augmentation for low-input bisulfite sequencing. Briefings in bioinformatics. 2021 Jul;22(4):bbaa332. (共一)
9、Li J, Zhao S, Lee M, et al. Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma. Science advances. 2020 Oct 16;6(42):eabb5427. (第一作者)
10、Guo L, Li J, et al. A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Nature communications. 2020 Feb 6;11(1):740. (共一)