主持的科研项目：

1、受体表达增强蛋白诱导非小细胞肺癌上皮间质转化和促进肿瘤侵袭转移的分子机制，国家自然科学基金面上项目，项目负责人；

miR-587 在非小细胞肺癌内持续性激活NF-kB信号通路的正反馈网络调控机制及生物学功能，国家自然科学基金青年科学基金项目，项目负责人；

2、肺癌转移分子机制的探讨:寻找诱导肿瘤上皮间质转化的关键调控因子，广东省自然科学基金杰出青年项目，项目负责人；

miR-587在非小细胞肺癌内持续性激活NF-kB信号通路的正反馈调控机制，广州市科技计划项目珠江科技新星专项，项目负责人；

3、原癌基因AEG-1在肿瘤干细胞自我更新中的生物学功能及分子机制，广东省自然科学基金博士启动项目，项目负责人；

4、原癌基因AEG-1促进胶质瘤血管新生的分子机制，中国博士后科学基金面上项目，项目负责人。

代表性学术论文：

1、Luo, Jiaqi; Liu, Liping; Chen, Lingxi; Xu, Xin; Wang, Yanfei; Wei, Bing; Ju, Chunrong; Wang, Xuedong; Huang, Liyan; Zeng, Wenchuang; Miao, Xinyao; Sang, Ling; Huang, Danxia; Pan, Guangze; Peng, Guilin; Chen, Zhuxing; Zhao, Zicheng; Yang, Chao; Cui, Weixue; Jiang, Wenxi; Xu, Jinjin; Li, Shuai Cheng; He, Jianxing*. Over-shedding of donor-derived cell-free DNA at immune-related regions into plasma of lung transplant recipient. Clinical and Translational Medicine, 2022, 12(1): 0-e622.

2、Zhuxing Chen, Liping Liu, Feng Zhu, Xiuyu Cai, Yi Zhao, Peng Liang, Limin Ou , Ran Zhong , Ziwen Yu , Caichen Li , Jianfu Li , Shan Xiong , Yi Feng , Bo Cheng , Hengrui Liang , Zhanhong Xie , Wenhua Liang , Jianxing He. Dynamic monitoring serum tumor markers to predict molecular features of EGFR-mutated lung cancer during targeted therapy. Cancer Med. 2022 Aug;11(16):3115-3125. doi: 10.1002/cam4.4676. Epub 2022 May 11.

3、Yuan Qiu, Liping Liu, Haihong Yang, Hanzhang Chen, Qiuhua Deng, Dakai Xiao, Yongping Lin, Changbin Zhu, Weiwei Li, Di Shao, Wenxi Jiang, Kui Wu, Jianxing He. Intratumor heterogeneity of driver mutations and TMB distribution in 30 early-stage LUAD patients with multiple lesions. Front Oncol. 2022 Aug 30;12:952572. doi: 10.3389/fonc.2022.952572. eCollection 2022.

4、Yuan Qiu, Liping Liu, Haihong Yang, Hanzhang Chen, Qiuhua Deng, Dakai Xiao, Yongping Lin, Changbin Zhu , Weiwei Li , Di Shao, Wenxi Jiang, Kui Wu , Jianxing He.Integrating Histologic and Genomic characteristics to Predict Tumor Mutation Burden of Early-stage Non-Small-Cell Lung Cancer. Front Oncol. 2021 Apr 30;10:608989.

5、Xu, Zijun; Xu, Lijuan; Liu, Liping; Li, Hai; Jin, Jiewen; Peng, Miaoguan; Huang, Yanrui; Xiao, Haipeng; Li, Yanbing; Guan, Hongyu. A Glycolysis-Related Five-Gene Signature Predicts Biochemical Recurrence-Free Survival in Patients With Prostate Adenocarcinoma. Frontiers in Oncology, 2021, 11: 0-625452.  

6、Zijun Xu, Lijuan Xu, Liping Liu, Hai Li, Jiewen Jin, Miaoguan Peng, Yanrui Huang, Haipeng Xiao, Yanbing Li, Hongyu Guan. A Glycolysis-Related Five-Gene Signature Predicts Biochemical Recurrence-Free Survival in Patients With Prostate Adenocarcinoma. Front Oncol. 2021 Apr 19;11:625452. doi: 10.3389

7、Liu LP, Lin CY, Liang WJ, Wu S, Liu AB, Wu JH, Zhang X, Ren PL, Li MF, Song LB. TBL1XR1 promotes lymphangiogenesis and lymphatic metastasis in esophageal squamous cell carcinoma. Gut. 2015 Jan;64(1):26-36.

8、Liu LP, Chen K, Wu JH, Shi L, Hu B, Cheng SY, Li MF, Song LB. Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas. Clinical Cancer research. 2013;19(13):3429-38.

9、Song LB, Liu LP, Wu ZQ, Li Y, Ying Z, Lin CY, Wu JH, Hu B, Cheng SY, Li MF, Li J. TGF-beta induces miR-182 to sustain NF-kappa B activation in glioma subsets. J Clin Invest. 2012; 122(10):3563– 3578.

10、Song LB, Liu LP, Wu ZQ, Lin CY, Dai T, Yu CP, Wang X, Wu JH, Li MF, Li J. Knockdown of stomatin-like protein 2 (STOML2) reduces the invasive ability of glioma cells through inhibition of the NF-kappa B/MMP-9 pathway. Journal of pathology. 2012;226(3):534-543.

11.、Liu LP, Wu JH, Ying Z, Chen BX, Han AJ, Liang YJ, Song LB,Yuan J, Li J, Li, MF. Astrocyte Elevated Gene-1 Upregulates Matrix Metalloproteinase-9 and Induces Human Glioma Invasion. Cancer research.2010;70(9):3750-3759.