全体研究人员 学组负责人

唐潇潇

职称:

教授

研究方向:

间质性肺病和肺血管病

研究工作:

肺损伤与肺纤维化等呼吸疾病发病机制与防治策略

科研项目:

1、中组部国家高层次人才项目,主持,2017-2020

2、国家自然科学基金面上项目(81770015),主持,2018-2021

3、国家自然科学基金面上项目(82270077),主持,2023-2026

4、广东省珠江人才计划本土创新科研团队项目,核心成员,2018-2023

5、广东省科技厅新冠肺炎应急攻关项目,子课题负责人,2020-2021

代表性学术论文:

1、Yang Peng # , Shi-ying Chen # , Zhao-ni Wang # , Zi-qing Zhou # , Jing Sun # , Gui-an Zhang # , Jia Li, Lei Wang, Jin-cun Zhao, Xiao Xiao Tang*, De-Yun Wang*, Nan-shan Zhong*. Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human respiratory epithelium (2023). Signal Transduction and Targeted Therapy. 8(1):242.

2、Zhao Ni Wang, Xiang Sheng Yang, Xin Xu, Qing Yang Yu, Yang Peng, Jian Xing He, Nan Shan Zhong*, Xiao Xiao Tang*. Induction of CTGF accounts for the inability of glucocorticoid suppression on lung fibrosis (2022). Clinical and Translational Medicine. 12(5):e867. doi: 10.1002/ctm2.867.

3、Zhao Ni Wang#, Xiang Sheng Yang#, Jing Sun#, Jin Cun Zhao, Nan Shan Zhong, Xiao Xiao Tang*. Multi-omics evaluation of SARS-CoV-2 infected mouse lungs reveals dynamics of host responses (2022). iScience. 25(3):103967. doi: 10.1016/j.isci.2022.103967.

4、Guichuan Huang#, Xin Xu#, Chunrong Ju#, Nanshan Zhong*, Jianxing He*, Xiao Xiao Tang*. Identification and validation of autophagy-related gene expression for predicting prognosis in patients with idiopathic pulmonary fibrosis (2022). Frontiers in Immunology. doi: 10.3389/fimmu.2022.997138.

5、Yixin She#, Xin Xu#, Qingyang Yu, Yangsheng Yang, Jianxing He*, Xiao Xiao Tang*. Elevated expression of macrophage MERTK exhibits profibrotic effects and results in defective regulation of efferocytosis function in pulmonary fibrosis (2023). Respiratory Research. 24(1): 118. doi.org/10.1186/s12931-023-02424-3.

6、Yichun Wang#*, Diyu Chen#, Han Xie, Shuhua Zhou, Mingwang Jia, Xiaobo He, Feifei Guo, Yihuan Lai, Xiao Xiao Tang*. LncRNA GAS5 suppresses TGF- β 1-induced transformation of pulmonary pericytes into myofibroblasts by recruiting KDM5B and promoting H3K4me2/3 demethylation of the PDGFRα/β promoter (2023). Molecular Medicine. 29(1):32. doi: 10.1186/s10020-023-00620-x.

7、Qing Yang Yu, Xiao Xiao Tang*. Irreversibility of pulmonary fibrosis (2022). Aging and Disease. 13(1):73-86. http://dx.doi.org/10.14336/AD.2021.0730. 8. Wei Jie Huang, Xiao Xiao Tang*. Virus Infection Induced Pulmonary Fibrosis (2021). Journal of Translational Medicine. 19(1):496. doi: 10.1186/s12967-021-03159-9.

获奖及个人荣誉:

1、中组部国家高层次人才项目入选者

2、国家高层次留学人才

3、广东省杰出青年医学人才

4、广东省珠江人才计划本土创新科研团队核心成员

5、广州市医学重点人才

6、广州市优秀专家

7、广东省劳模和工匠人才创新工作室(肺纤维化创新研究工作室)负责人(2022)

8、创新工作室十大创新成果榜首(2022)

9、广州榜样·抗疫劳动者(2020)

10、广医好能手(2020)

11、广州医科大学三八红旗手标

联系方式:

Email: tangxiaoxiao@gird.cn