全体研究人员 学组负责人

唐潇潇

职称:

教授

研究方向:

间质性肺病/肺纤维化研究方向负责人

研究工作:

肺损伤与肺纤维化等呼吸疾病发病机制与防治策略的基础与转化研究

科研项目:

1、国家高层次人才项目,主持,2017-2020

2、国家自然科学基金面上项目 (3项,先后主持)

3、广东省珠江人才计划本土创新科研团队项目,核心成员,2018-2023

4、广东省科技厅新冠肺炎重大应急攻关项目,子课题负责人,2020-2021

部分通讯作者学术论文:

1、Overexpression of STX11 alleviates pulmonary fibrosis by inhibiting fibroblast activation via the PI3K/AKT/mTOR pathway (2024). Signal Transduction and Targeted Therapy. 9(1):306.

2、Induction of CTGF accounts for the inability of glucocorticoid suppression on lung fibrosis (2022). Clinical and Translational Medicine. 12(5):e867.

3、Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human respiratory epithelium (2023). Signal Transduction and Targeted Therapy. 8(1):242.

4、Multi-omics evaluation of SARS-CoV-2 infected mouse lungs reveals dynamics of host responses (2022). iScience. 25(3):103967.

5、Elevated expression of macrophage MERTK exhibits profibrotic effects and results in defective regulation of efferocytosis function in pulmonary fibrosis (2023). Respiratory Research. 24(1):118.

6、IdentIfication and validation of autophagy-related gene expression for predicting prognosis in patients with idiopathic pulmonary fibrosis (2022). Frontiers in Immunology.13:997138.

7、LncRNA GAS5 suppresses TGF-β1-induced transformation of pulmonary pericytes into myofibroblasts by recruiting KDM5B and promoting H3K4me2/3 demethylation of the PDGFRα/β promoter (2023). Molecular Medicine. 29(1):32.

8、Role of ADAM and ADAMTS proteases in pathological tissue remodeling (2023). Cell Death Discovery.9(1):447.

9、Irreversibility of pulmonary fibrosis (2022). Aging and Disease. 13 (1): 73-86.

10、Virus infection induced pulmonary fibrosis (2021). Journal of Translational Medicine. 19(1): 496.

11、Role of interleukins in the pathogenesis of pulmonary fibrosis (2021). Cell Death Discovery. 7(1): 52.

12、Regulation of macrophage activation by lactylation in lung disease (2024). Frontiers in Immunology.15:1427739.

主要学术任职:

1、中国生理学会呼吸生理专业委员会委员

2、中国研究型医院学会呼吸病学专业委员会委员

3、中国罕见病联盟呼吸病学分会委员

4、教育部学位中心评审专家

5、Science子刊Science Translational Medicine、柳叶刀子刊The Lancet Regional Health-Western Pacific、Metabolism-clinical and experimental、Advanced science、Acta pharmaceutica sinica B等国际SCI期刊同行评议专家

获奖及个人荣誉:

1、国家高层次人才

2、国家高层次留学人才

3、广东省杰出青年医学人才

4、广东省劳模和工匠人才创新工作室(肺纤维化创新研究工作室)负责人

5、广东省珠江人才计划本土创新科研团队核心成员

6、广州市医学重点人才

7、广州市优秀专家

8、广州榜样·抗疫劳动者

9、创新工作室十大创新成果榜首

10、广州医科大学三八红旗手标兵

11、广州医科大学好能手

联系方式:

Email: tangxiaoxiao@gird.cn