导师介绍
| 姓名 | 门冬 | 性别 | 男 |
| 民族 | 汉族 | 导师层次 | 博士生导师 |
| 职称 | 研究员 | 导师类型 | 学术型 |
| 学历 | 研究生 | 学位 | 博士 |
| 行政职务 | 无 | 邮箱 | men_dong@gzlab.ac.cn |
| 招生方向 | |||
门冬，广州医科大学特聘教授，广州国家实验室检测与诊疗技术研究部研究员，病原检测与抗体筛选学科组组长。2011年于中国科学院武汉病毒研究所获博士学位，并获得中国科学院院长奖、中国科学院优秀博士学位论文等奖项。2011-2022年在中国科学院武汉病毒研究所工作，历任副研究员、研究员、学科组长。
主要围绕国民健康的重大需求，进行先进生物技术和信息技术的交叉研究，发展快速、灵敏、准确的生物分析/生物传感新技术、新方法与新产品。在自组装纳米器件、微流控芯片和病原检测技术中获得创新成果。在ACS nano, Nat. Comm., Biosens. Bioelectron.等国际学术期刊发表论文61篇，申请国家发明专利44项（授权21项）。主持的项目（课题）包括国自然青年、面上，国家重大科技项目，国家重点研发计划，中科院创新基金，中科院重点部署等。曾获世界生物传感器大会最具原始创新奖，湖北省自然科学优秀学术论文特等奖，中国科学院优秀博士学位论文，湖北省自然科学一等奖，中科院优秀青促会会员等奖项。
1、基于合成生物学、纳米生物学的新型疾病检测技术
2、基于微流控芯片与新型传感器件的生物传感系统
3、基于人工智能的生物大分子理性设计
1、Yingya Liu#, Jihang Zhai, Shanshan Cao, Huiying Guo, Hengwei Zhang, Bo Song, Jiajia Guo, Dong Men*, Xiao He*, Di Li*. Single-engineered-residue solvation perturbations regulate global protein architecture and function. Nat Commun 17, 3754 (2026).
2、Zheng Y, Zhang CY, Zhang Y, Zhou K, Tan PW, Liu YJ, Duan GT, Li HF, Chen CL, Guo CL, Li XD, Chen C, Ashaq Ali, Zhang Y*, Zhang XE*, Men D*. A Nanomaterial-Independent Biosensor Based on Gallium Arsenide High-Electron-Mobility Transistors for Rapid and Ultra-Sensitive Pathogen Detection. ACS Sens. 2025 Jun 27;10(6):3898-3908.
3、Zhou K, Zhou J, Cao S, Zheng Y, Zhang XY, Chen C, Zhang XE*, Men D*. Bifunctional Protein TC1 Mediated One-Pot Strategy for Robust Immobilization of DNA with High Accessibility. Small Methods. 2024 Dec;8(12):e2400049.
4、Feng XY, Gao D, Zhou J, Gui Z, Cai AL, Wang J, Dai J, Jing YP, Qian JC, Cui ZQ, Li LX, You Y, Tian LY, Zhang XE*, Dong Men D*. Viral capsid-mediated efficient cell labeling of micron-sized magnetic particles for highly sensitive long-term in vivo tumor cells MRI tracking. Chemical Engineering Journal. 2024 498(155830).
5、Lin Y, Yang M, Huang L, Yang F, Fan J, Qiang Y, Chang Y, Zhou W, Yan L, Xiong J, Ping J, Chen S, Men D*, Li F*. A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase. Cell Rep. 2023 Nov 28;42(11):113453.
6、Chen C, Zhou J, Men D*, Zhang XE*. Promoter-regulated in vivo asymmetric self-assembly strategy to synthesize heterogeneous nanoparticles for signal amplification. Nanoscale. 2022 Nov 10;14(43):16180-16184.
7、Feng X#, Gao D#, Jing Y, Qian J, Cui Z, Zhou J, Zhang XE*, Men D*. Intracellular Delivery of Micron-Sized Magnetic Particles through a Virus Infection Pathway. ACS Appl Mater Interfaces. 2022 Oct 19;14(41):46850-46856.
8、Wei CH, Zhou J, Liu TG, Zhao WQ, Zhang XE*, Men D*. Self-Assembled Enzymatic Nanowires with a “Dry and Wet” Interface Improve the Catalytic Performance of Januvia Transaminase in Organic Solvents[J]. ACS Catalysis, 2021, 12: 372-382.
9、Jiang HW, Li Y, Zhang HN, Wang W, Yang X, Qi H, Li H, Men D*, Zhou J*, Tao SC*. SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses. Nat Commun. 2020 Jul 14;11(1):3581.
10、Li Y, Zhou J, Song J, Liang X, Zhang Z, Men D*, Wang D, Zhang XE*. Chemical nature of electrochemical activation of carbon electrodes. Biosens Bioelectron. 2019 Nov 1;144:111534.
11、Men D, Zhang TT, Hou LW, Zhou J, Zhang ZP, Shi YY, Zhang JL, Cui ZQ, Deng JY, Wang DB, Zhang XE*. Self-Assembly of Ferritin Nanoparticles into an Enzyme Nanocomposite with Tunable Size for Ultrasensitive Immunoassay. ACS Nano. 2015 Nov 24;9(11):10852-60.
12、Men D, Zhang ZP, Guo YC, Zhu DH, Bi LJ, Deng JY, Cui ZQ, Wei HP, Zhang XE. An auto-biotinylated bifunctional protein nanowire for ultra-sensitive molecular biosensing. Biosens Bioelectron. 2010 Dec 15;26(4):1137-41.
13、Men D, Guo YC, Zhang ZP, Wei HP, Zhou YF, Cui ZQ, Liang XS, Li K, Leng Y, You XY, Zhang XE. Seeding-induced self-assembling protein nanowires dramatically increase the sensitivity of immunoassays. Nano Lett. 2009 Jun;9(6):2246-50.
