代表性科研项目：

1、建立华南地区最大的ILD数据库。作为子课题负责人参与卫生部精准医学研究重点专项“常见间质性肺病基础数据平台的建立（2016YFC0905701）”和“社区队列呼吸疾病筛查及间质性肺疾病专病队列研究（2016YFC0901101）”，建立了ILD患者完善的临床数据资料及生物标本数据库，为研究开展提供临床实践基础，其中以通讯作者发表论文1篇（J Thorac Dis. 2020 Jul;12(7):3688-3696）.作为课题负责人主持广实科研任务专项项目“特发性肺纤维化精准诊断、发病机制及新型”，本项目旨在建立IPF精准诊断模型以及肺纤维化活动评估方法，阐明IPF致病机制，并研发重塑病理生态位的新型有效策略，为IPF的精准诊断及治疗提供重要基础。目前以通讯作者发表论文1篇。

确定SLB及TBLC活检方式的选择及开展ILD患者MDD。根据ILD患者HRCT病灶部分、性质，选择不同的活检方式可提高诊断有效率及提高MDD讨论一致率。以通讯/第一作者共发表论文4篇。（J Thorac Cardiovasc Res. 2015. 149(5):1394–1401；Heart Lung Circ 2014 Aug;23；Clini Respir J. 11(2):168-175；Sci Rep. 2019 23;(1):6452），其中2篇获2018年国际IPF诊疗指南引用（J Thorac Cardiovasc Res. 2015. 149(5):1394.以及J Thorac Dis. 2013:5(3):283.）,这也是首次国内相关论文被国际IPF诊疗指南引用。

代表性学术论文（参考文献格式）：

1、Fang Q, Hou P, Xia S, Zhong S, Zhao R, Liang W, Cui J, He Y, Bai X, Li Y, Zhang Z, Fu Z, Liu S, Lv J, Guo B, Fu Y, Zhong H, Zhong N, Han Q, Luo Q, Wang X. [18F]FAPI-42 PET/CT for prognostic assessment in idiopathic pulmonary fibrosis: a prospective head-to-head comparison with [18F]FDG PET/CT. Eur J Nucl Med Mol Imaging. 2026 Jul 30. doi: 10.1007/s00259-026-08094-9. Epub ahead of print. PMID: 42530577.

2、Zhang, Ziyi; Ma, Xiaogian; Bai, Junye; Xia, Shu; Han, Qian"; Luo, Qun ; Characterizing the lavage and serum cytokine profiles of interstitial pneumonia with autoimmune features andtheir implications for progressive fibrosis, Rheumatology, 2024, 63(5): 1230-1239(期刊论文)

3、Zhong, Jiaying; Li, Juan; Wei, Rui; Guo, Bingpeng; Cui, Tingting; Huang, Peiyu; Wang,Zhongfang; Luo, Qun"; Han, Qian* ; Delayed Viral Clearance Accompanied by Early Impaired Humoraland Virus-Specific T-Cell Response in Patients with Coronavirus Disease 2019 and InterstitialLung Disease, Vaccines, 2025, 13 (6): 0-655(期刊论文)

4、Lin, Qiuxi; Zhang, Ziyi; Xiong, Xirui; Chen, Xilai; Ma, Ting; Chen, Yibin; Li, Ting;Long, Zhenchu; Luo, Qun*: Sun, Yan; Jiang, Lihong; He, Wei; Deng, Yu* : nnU-Net-based high-resolution CT features quantification for interstitial lung diseases, European Radiology, 2025.35(11):7140-7149(期刊论文)

5、Huang, Xihui; Xia, Shu; Yang, Yiqian; Lei, Chengcheng; Yang, Penghui; Li, Shuang; Niu,Jianyi; Wu, Jian; Luo, Qun"; Fu, Zhenli ; Unilateral Lung Volume Analysis Using Micro-CT forEnhanced Assessment of Pulmonary Fibrosis in Preclinical Models, Jove-Journal of VisualizedExperiments, 2025, (220): 0-e67837(期刊论文)

6、Lian, Qiao-yan; Chen, Ao; Zhang, Jian-heng; Xu, Xin; Huang, Dan-xia; Luo, Qun : He, Jian-xing: Ju, Chun-rong : Lung transplantation for anti-MDA5-positive dermatomyositis-associatedrapid progressive interstitial lung disease: report of two cases and review of the literature,Clinical Rheumatology, 2023, 42 (3): 941-947(期刊论文)

7、Jing, Xiaoyan; Sun, Wei; Yang, Xiaoyu; Huang, Hui; Wang, Ping; Luo, Qun; Xia, Shu; Fang.Chul ing; Zhang, Qian; Guo, Jian; Xu, Zuojun : CCAAT/enhancer-binding protein (C/EBP) homologousprotein promotes alveolar epithelial cell senescence via the nuclear factor-kappa B pathway inpulmonary fibrosis, International Journal of Biochemistry & Cell Biology, 2022, 143: 0-106142（期刊论文)

8、Sun, Wei; Liu, Xiaoshu; Yang, Xiaoyu; Jing, Xiaoyan; Duan,Ganghao; Wu,Chunyan; Yang,Chi; Huang, Hui; Luo, Qun; Xia, Shu; Zhang, Qian; Yang, Yang ; Xu, Zuojun : SENP1 regulates thetransformation of lung resident mesenchymal stem cells and is associated with idiopathicpulmonary fibrosis progression, Cell Communication and Signaling, 2022, 20(1) : 0-104(期刊论文)

9、Fang, Qi; Liu, Shaoyu; Cui, Jiangyu; Zhao, Ruiyue; Han, Qian; Hou, Peng;: Li, Youcai; Lv,Jie; Zhang, Xiaoyao; Luo, Qun ; Wang, Xinlu ; Mesoporous Polydopamine Loaded Pirfenidone Targetto Fibroblast Activation Protein for Pulmonary Fibrosis Therapy, Frontiers in Bioengineering andBiotechnology, 2022, 10: 0-920766(期刊论文)

10、Penghui Yang"; Qi Fang"; Zhenli Fu"; Jia Li"; Yunxin Lai"; Xiaobo Chen"; Xin XuF; XiaominPeng"; Kongzhen Hu"; Xiaowei Nie; Shaoyu Liu; Jinhe Zhang; Jungi Li; Chenyou Shen; Yingying Gu;Jianping Liu; Jingyu Chen; Nanshan Zhong; Xinlu Wang ; Qun Luo; Jin Su* : Comprehensive Analysisof Fibroblast Activation Protein (FAP) Expression in Interstitial Lung Diseases (ILDs), AmericanJournal of Respiratory and Critical Care Medicine, 2022, 207 (2) : 160-172(期刊论文)

11、Han, Qian; Chen, Xiaobo; Xu, Xin; Qian, Weiping; Zhao, Gui; Mao, Mengmeng; Guo,Bingpeng; Xia, Shu; Peng, Guilin; He, Jianxing; Gu, Yingying; Li, Shiyue"; Luo, Qun* : TheApplication of Transbronchial Lung Cryobiopsy and Uniportal and Tubeless Video-Assisted ThoracicSurgery in the Multidisciplinary Diagnosis of Interstitial Lung disease-A Real-World ProspectiveStudy, Frontiers in Molecular Biosciences, 2021, 8: 0-681669(期刊论文)

12、Han Q, Wang HY, Zhang XX, Wu LL, Wang LL, Jiang Y1, Deng KM, Mao MM, Chen RC, Kolb M, Luo Q. The Role of Follow-up Evaluation in the Diagnostic Algorithm of  Idiopathic Interstitial Pneumonia: A Retrospective Study. Sci Rep. 2019 23;(1):6452(IF=4.011)

13、Q Han, Q Luo, XB Chen, JX Xie, LL Wu and RC Chen. The evaluation of clinical usefulness of transbrochoscopic lung biopsy in undefined interstitial lung diseases: a retrospective study. Clini Respir J. 2017. 11(2):168-175.(IF=1.751)

14、Jiang Y, Luo Q, Han Q, Huang J, Ou Y, Chen M, Wen Y, Mosha SS, Deng K, Chen R. Sequential changes of serum KL-6 predict the progression of interstitial lung disease. J Thorac Dis. 2018 Aug;10(8):4705-4714.(IF=2.027)

15、谢姿,罗群.早期一线联合托法替布治疗重症抗黑色素瘤分化相关基因-5抗体阳性皮肌炎相关快速进展型间质性肺炎1例并文献复习[J].实用检验医师杂志,2023,15(01):97-102.

16、韩茜,罗群.尼达尼布治疗纤维化性间质性肺疾病的研究综述[J].临床肺科杂志,2023,28(12):1908-1914.

17、崔江禹, 郭炳鹏, 罗群, 等.  抗MDA5阳性皮肌炎相关间质性肺病并自发性出血2例 [J/OL] . 中国临床案例成果数据库, 2022, 04(1) : E03543-E03543. DOI: 10.3760/cma.j.cmcr.2022.e03543.

18、黄伟华,王春燕,罗群,等.36例肺朗格汉斯细胞组织细胞增生症临床分析[J].结核与肺部疾病杂志,2021,2(02):131-138.

19、韩茜,罗群.肺活检在特发性肺纤维化诊断中的应用[J].中国临床新医学,2021,14(04):345-349.